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Scientific Library: Aspartame and Safety

A. de la Hunty, S. Gibson, M. Ashwell
This review has shown that using foods and drinks sweetened with aspartame instead of those sweetened with sucrose is an effective way to maintain and lose weight without reducing the palatability of the diet.
Arthur S. Leon, MD; Donald B. Hunninghake, MD; Catherine Bell, MBA; David K. Rassin, PhD; Thomas R. Tephly, MD, PhD
These results further document the safety of the long-term consumption of aspartame at doses equivalent to the amount of aspartame in approximately 10 L of beverage per day.
Susan S. Schiffman, Ph.D., C. Edward Buckley III, M.D., H.A. Sampson, M.D., E.W. Massey, M.D., J.N. Baraniuk, M.D., J.V. Follett, M.D., and Z.S. Warwick,B.S.
It was concluded that in this population, aspartame is no more likely to produce headache than placebo.
James Rowan, *Bennett A. Shaywitz, Linda Tuchman, Jacqueline A. French, Daniel Luciano, and *Colleen M. Sullivan
Aspartame, in acute dosage of ~50 mg/kg, was found to be no more likely than placebo to cause seizures in individuals who reported that their seizures were provoked by aspartame consumption.
B. A. Shaywitz, MD, G. M. Anderson, PhD, E. J. Novotny, MD, J. S. Ebersole, MD, C. M. Sullivan, MSN, and S. M. Gillespie, MSN
The findings of this study indicate that, in this group of vulnerable children, APM does not provoke seizures.
James G. Gurney, Janice M.Pogoda, Elizabeth A. Holly, Stephen S. Hecht, Susan Preston-Martin
This review revealed little biologic or experimental evidence that aspartame is likely to act as a human brain carcinogen.
Paul A Spiers, LuAnn Sabounjjan, Allison Reiner, Diane K Myers, Judith Wurtman, and Donlad L Schomer
Large daily doses of aspartame had no effect on neuropsychologic, neurophysiologic, or behavioral functioning in healthy young adults.
Lewis D. Stegink, L.J. Filer, Jr, Edward F. Bell, Ekhard E. Ziegler, and Thomas R. Tephly
The data indicate ready metabolism of APM when administered at levels that may be ingested by normal individuals who are heavy users of diet beverages.
Anne Raben, Tatjana H Vasilaras, A Christina M├śller, and Arne Astrup
Overweight subjects who consumed artificial sweeteners did not have increased energy intake, body weight, fat mass and blood pressure after 10 wk.
M.E. Beridot-Therond, Arts and M. Fantino
Subjects presented with non-sweetened and sweetened beverges consumed slightly more of the sweetened beverages.